Liverpool host West Ham United on Saturday looking to record a third successive win over the Hammers for the first time since November 2010.
Reds boss Jürgen Klopp got the better of Slaven Bilic when the two sides last met but there will be a new manager in the opposition dugout for this Premier League encounter.
David Moyes assumed the Irons throne in November last year and will be seeking to achieve something with his new club that he never managed with previous sides Everton, Manchester United and Sunderland: win at Anfield.
Here's how Liverpool have fared in the last 10 matches against West Ham...
1. Salah at the double
This was the 14th time under Klopp that Liverpool had scored four or more goals in a single Premier League game and it could have been an even greater margin of victory for the dominant Reds at the London Stadium.
Mohamed Salah continued the phenomenal start to his Anfield career with a brace that meant he had scored or assisted 15 goals in his first 17 games for Liverpool.
Meanwhile, Sadio Mane marked his return from injury by setting up both goals for the Egyptian.
2. Reds on the rise
Klopp's Reds recorded their biggest win at West Ham for 41 years in the penultimate match of the 2016-17 season to all but confirm a top-four finish and a return to Champions League football.
Philippe Coutinho scored a brace and set up Daniel Sturridge for the opener to help secure a victory at the London Stadium that meant LFC had triumphed at 52 different grounds in the Premier League - more than any other side.
3. Origi pounces to earn Liverpool point
Liverpool played some brilliant football in this winter clash at Anfield but frailties at the back saw the match end in a draw.
The Reds recorded 59 touches in the opposition box, their most in a Premier League game at that point in the season, while West Ham registered just five.
Despite those statistics, only Divock Origi's 48th-minute finish from Darren Randolph's goalkeeping error eventually secured a point for Klopp's men.
4. Signing off from Upton Park
Coutinho's clever, low free-kick under the wall sent this FA Cup replay into extra-time and both sides hit the woodwork before Angelo Ogbonna headed home a late, late winner.
This was Liverpool's 40th game in all competitions in 2015-16 - more than any other Premier League team - and their final ever trip to Upton Park before the Hammers moved to the London Stadium.
5. Young Reds up for the cup
West Ham goalkeeper Randolph - who had made his Charlton Athletic debut at Anfield in 2007 and denied Robbie Fowler a goal on his final LFC appearance - was in inspired form in this one, making six top saves to deny Joao Teixeira, Cameron Brannagan, Joe Allen and Christian Benteke.
With Liverpool facing a fifth game in the space of 13 days, Klopp made 10 changes and fielded a youthful starting XI with an average age of 23.78 for this FA Cup fourth-round tie.
6. Shooting gallery
Emre Can hit the bar with a curling shot from the edge of the penalty area and Lucas Leiva had a late effort cleared off the line during a match that featured an amazing 41 shots.
However, Andy Carroll's trademark header against his former club secured West Ham's first league double over Liverpool for 52 years.
7. Reds off colour
Danny Ings made his Liverpool debut in this one, but Coutinho was sent off and the Liverpool defence conceded their first goals of the season as Brendan Rodgers' Reds suffered a maiden defeat of the Premier League campaign.
8. Supersub Sturridge lifts Liverpool
Sturridge scored on his comeback from a five-month injury layoff as the Reds secured a fifth win in six Premier League games to move up the table.
On as a substitute for Lazar Markovic, Sturridge fired home 12 minutes into his return to ensure Rodgers' revived Reds headed into the upcoming Merseyside derby in top form.
9. Reds record, but no points
Raheem Sterling's strike saw Liverpool set a club record of scoring in 17 successive top-flight matches on the road, but it wasn't enough to secure a share of the points against Sam Allardyce's Hammers.
10. Spot-on Gerrard
Steven Gerrard scored a pair of penalties in this one to move ahead of Kenny Dalglish in Liverpool's all-time top goalscorers list.
The skipper climbed up to sixth, with 173 goals, and also moved level with Jan Molby as Liverpool's top goalscorer from the spot with 42 penalties.