Roberto Firmino will become the first Brazilian to score 50 Premier League goals if he nets against Arsenal on Saturday.
The No.9 bagged a hat-trick in the equivalent fixture at Anfield last season and has struck more goals against the Gunners than any other team - scoring eight times in eight outings.
Two goals for Firmino on Saturday would also see him become Liverpool's most prolific scorer against Arsenal in league history. Gordon Hodgson and Robbie Fowler are currently tied in first place on nine goals.
For more need-to-know pre-match facts and figures, courtesy of club statistician Ged Rea, read on...
Liverpool's 54 Premier League encounters with Arsenal have produced 155 goals. It is the highest-scoring Reds fixture in the competition - equal with their games against Tottenham Hotspur.
The Reds have won four of the last six meetings and are unbeaten in the last eight, with four victories and four draws.
Liverpool have not gone unbeaten in nine successive league fixtures against the Gunners since February 2000, which came in a sequence of 12.
The last 11 clashes with Arsenal in the Premier League have produced 50 goals - an average of 4.5 goals per game.
The Reds have scored 22 times in the last six league clashes on Merseyside and have won the last three by margins of 3-1, 4-0 and 5-1.
Liverpool have scored from the 90th minute onwards against Arsenal in three of the last five Anfield fixtures. The games have produced 17 goals in added time in the Premier League era.
Sadio Mane has found the net in nine of his last 11 Anfield league appearances, scoring 13 goals in the process. In this calendar year, he has scored 20 goals in 28 home and away appearances for the Reds in all competitions.
The Senegalese has scored four times in six appearances for Liverpool against the Gunners.
Jordan Henderson could captain Liverpool for the 100th time in the Premier League on Saturday.
Last season saw the Reds score four or more goals against the Gunners in successive home league encounters for the first time since 1922. They have never done so three seasons in a row.
Liverpool have now won 11 league games in a row - equalling their Premier League record. A victory on Saturday will see them match their all-time club league record of 12, which was set from April to October in 1990.