Dirk Kuyt needs just one goal to make it 50 in the league for Liverpool.
Only Robbie Fowler (128), Michael Owen (118), Steven Gerrard (84) and Fernando Torres (65) have scored more Premier League goals for the Reds.
If Liverpool's No.18 scores on Sunday he will record his 16th of the season in all competitions - his best tally in a Reds shirt beating the 15 he netted 2 seasons ago. He now has 13 goals from his last 14 appearances for Liverpool and Holland.
He could become the first Liverpool player ever to score in six successive Premier League games.
The Dutchman has also netted four league goals in nine appearances against Spurs.
Here are all the facts and figures ahead of Sunday's final Anfield game of 2010-11 from club statto Ged Rea.
Head to Head: (League Only)
At Anfield: Liverpool 43 wins, 19 draws, Tottenham 5 wins.
Overall: Liverpool 63 wins, 34 draws, Tottenham 38 wins.
Victory will guarantee Liverpool fifth place and a Europa League spot for next season.
Liverpool go into this game on the back of a five match unbeaten run - currently the longest of any team in the Premier League.
Back in November Liverpool lost 2-1 at White Hart Lane. Martin Skrtel put the Reds in front shortly before half time. Skrtel then put through his own net six minutes after Jermain Defoe had missed a penalty on the hour mark with Aaron Lennon scoring the winner in the second minute of stoppage time.
Last season's meeting here saw a depleted Reds' side win 2-0 with Dirk Kuyt scoring both goals, the second coming from the penalty spot deep into stoppage time.
Liverpool are unbeaten in 16 league games at home to Spurs - winning 11 and drawing five, while they have suffered one loss to Tottenham in last 18 Anfield clashes.
The Reds last hat-trick against Spurs was scored by Phil Boersma at Anfield in 1974. It is the last of four scored against the Londoners in the league.
103 goals have been scored in the 37 Premier League meetings between the sides. Of the teams the Reds have faced in the top-flight since 1992-93 only the Newcastle fixture (108) has produced more.
Jamie Carragher has had the misfortune to score three own goals against Tottenham during his career.
Sotirios Kyrgiakos could play his 50th game for Liverpool in all competitions if selected.
If Maxi scores another hat-trick it will be his third in four league games and he would be the first man since Jack Balmer in 1946 to score in successive games.
He would be the first to do it in successive league games since Ian Rush in November 1982.
A victory for Liverpool will give them a total of 43 points won at home this season - one more than the total they amassed in 2009-10.
If the Reds win their final two games they will finish the campaign with 64 points - one more than last season.
Liverpool have scored in the last 18 league games since Wolves kept a clean sheet at Anfield back in December.
The Reds have scored 17 goals in the last five games and 14 in the last four at Anfield.
In 16 league games under Kenny Liverpool have a +21 goal difference. The first 20 games of the league campaign saw the Reds with a goal difference of -3.
Liverpool have lost only one of the last 104 league games at Anfield when they have scored the first goal. That came against Arsenal last season when the Reds lost 2-1.
With two games remaining this season, Liverpool have scored 59 goals. They totalled 61 in the whole of last season's league campaign.
Tottenham have won six away games this season in the Premier League - all by the odd goal. They have recorded victories at Stoke (2-1), Fulham (2-1), Arsenal (3-2), Aston Villa (2-1), Blackburn (1-0) and Sunderland (2-1).
Spurs have not won in the last six games in all competitions and just one of the last 13. In the Premier League their only win in the last 10 came when they beat Stoke 3-2 at home last month.
They have not kept a clean sheet in the last eight league and cup fixtures.
When Kenny Dalglish returned to management in January Tottenham were 11 points and eight places better off than Liverpool although the Reds did have a game in hand. As recently as six games ago they were eight points ahead of Liverpool. The Reds are now two points better off.
Of the last 16 Premier League games played Spurs have won only four, though they have drawn six of the last nine.
They have only been beaten three times in the last 15 top-flight games, though two of those have come in the last three.
Their last away win came in February when goals from Michael Dawson and Niko Kranjcar saw them come from behind to win 2-1 at Sunderland.
Last season Peter Crouch, Roman Pavlyuchenko and Jermain Defoe scored 31 league games between them. So far this season the trio have netted 16.
Heurelho Gomes has saved two penalties this season - at home to Chelsea and last weekend against Blackpool.
Peter Crouch made 134 appearances for Liverpool scoring 42 goals but never found the net for the Reds against his current club.
Ledley King made his Spurs debut on this ground 12 years ago this month, while Michael Dawson did likewise in April 2005.
Benoit Assou-Ekotto has scored just once for Tottenham. It came against Liverpool on the opening weekend of last season.
Spurs have scored only seven of the 12 penalties awarded to them this season.
This is the ninth time the two clubs have met in Liverpool's final home league fixture of a campaign. Of the previous meetings Liverpool have won seven and drawn one.
Since the inception of the Premier League Liverpool have won 17 and lost 10 of the 37 meetings home and away.
Last season Tottenham finished above Liverpool for the first time since 1970-71. The last time they achieved that for a second successive season when both clubs were in the same division was 1953-54.
Tottenham have done the double over Liverpool four times in their history and only twice since 1912. The last came in 1986-87 with current Spurs first team coach Clive Allen scoring the only goal of the game at Anfield.
Spurs have kept one clean sheet in the last 14 league visits to Anfield and two in the last 23 on this ground in the top-flight.
The Londoners' last league win here came on 25th August 1993 when Teddy Sheringham scored twice in a 2-1 victory. Since then they have picked up five points out of a possible 48.
However, they did record a 3-1 League Cup success here in 1998 with ex-Liverpool man John Scales amongst the scorers. It proved to be Roy Evans' last game in the Anfield hot seat.
Only two players have been sent off in Liverpool v Tottenham Barclays Premier League meetings - Mauricio Taricco (1995) and Paul Stalteri (2006) were both dismissed for the visitors at Anfield.
Tottenham's heaviest defeat at Anfield came in September 1978 when they lost 7-0. It is still the club's biggest ever League defeat.
All five of Tottenham's league wins on this ground have been by the odd goal.
Since 1912 Spurs have won only three times in 64 league meetings at Anfield. They came in 1985, 1986 and 1993.
Only Garth Crooks, Clive Allen and Teddy Sheringham have scored league goals in winning Tottenham teams at Anfield in the last 97 years.
Tottenham's last hat-trick against the Reds was scored by Jimmy Greaves who hit four at White Hart Lane in April 1963 in a 7-2 win.
Referee Howard Webb, who took charge of the Anfield fixture between the teams last season, received the MBE from Prince Charles at Buckingham Palace last Wednesday.
Scorers this season (league in brackets):
Liverpool: Kuyt 15 (13), Maxi 10 (10), Torres 9 (9), Gerrard 8 (4), Ngog 8 (2), Meireles 5 (5), Suarez 4 (4), Cole 3 (2), Babel 2 (1), Carroll 2 (2), Johnson 2 (2), Jovanovic 2 (0), Kyrgiakos 2 (2), Skrtel 2 (2), Lucas 1 (0), own goals 2 (1).
Tottenham: Van der Vaart 14 (12), Pavlyuchenko 12 (8), Bale 11 (7), Crouch 11 (4), Defoe 9 (4), Lennon 3 (3), Modric 3 (2), Bassong 2 (1), Huddlestone 2 (2), Hutton 2 (2), Kranjcar 2 (2), Kaboul 2 (1), Dawson 1 (1), Keane 1 (0), Sandro 1 (1), Townsend 1 (0), own goals 3 (1).