Kick-off at the Select Security Stadium in Widnes is at 5.30pm GMT, and the official matchday programme is the perfect souvenir for the fixture, on sale at the ground and includes exclusive interviews with some of the Reds' key personnel.
Wales captain Sophie Ingle reflects on the team's start to the season and outlines her personal goals, while we also catch up with assistant manager Phil Backhouse.
We hear the thoughts of manager Scott Rogers and skipper Gemma Bonner ahead of the clash with the Blues in their exclusive columns.
There is a profile of sister club Sandbach United including a full round-up of recent fixtures, the lowdown on our visitors from the Midlands and all the latest statistics too.
With all this and much more, make sure you pick up your copy of the official matchday programme which will be on sale inside the ground, priced £2.