The Swiss forward comes into the starting line-up in place of James Milner, while Roberto Firmino is restored to attack.
Elsewhere, Joel Matip is drafted in for Joe Gomez in the centre of defence.
Liverpool: Alisson, Alexander-Arnold, Matip, Van Dijk, Robertson, Wijnaldum, Henderson, Shaqiri, Mane, Salah, Firmino.
Subs: Mignolet, Fabinho, Milner, Keita, Gomez, Sturridge, Moreno.