The infectious chant, strains of which were first heard during the first leg of the last-16 win over FC Porto, has become synonymous with this year's thrilling run in the competition.
But this is not the first time that Reds supporters have soundtracked the club's European journeys in memorable fashion.
Take a musical walk down memory lane with some continental choruses from across the years...
1977 - We're On Our Way To Roma
Liverpool's first appearance in a European Cup final took them to the Eternal City for a meeting with Borussia Monchengladbach.
With the name of the opposition hardly conducive to a terrace chant, supporters instead took inspiration from the host city when penning a song for the showpiece fixture.
And they came up with the following, sung to the tune of 'Arrivederci Roma', which had been popularised by Dean Martin many years earlier.
We're on our way to Roma
On the 25th of May
Vatican bells will be ringing
All the Kopites will be singing
When we win the European Cup
1984 - I Don't Know What It Is But I Love It
Somewhat unusually, this one didn't originate in the stands but rather in the tunnel of the Stadio Olimpico, where Liverpool took on AS Roma in the 1984 final.
Joe Fagan's men faced the daunting task of overcoming the Italians on their home ground to secure the European Cup for the fourth time.
Determined not to show any fear as they prepared to walk out into a cauldron of noise, the men in red began belting out Chris Rea's recently released 'I Don't Know What It Is But I Love It' at the top of their lungs.
As defender Mark Lawrenson recalled to Goal.com: "The Roma players must have thought we were off our heads."
Liverpool went on to win a penalty shootout following a 1-1 draw, bringing the cup back to Anfield once more while cementing this song's place in the club's folklore.
2001 - Hou Led The Reds out
When Baha Men released their smash hit 'Who Let The Dogs Out' in the midst of a Liverpool season full of promise, opportunistic Kopites didn't miss their chance to adopt the undeniably catchy melody as a tribute to manager Gerard Houllier.
Few could have envisaged the 2000-01 campaign ending with the League Cup, FA Cup and UEFA Cup being added to the Anfield trophy cabinet, but it did so with this simplistic chant as its soundtrack.
Asked about the song, a humble Houllier said: "It's very embarrassing, to be honest.
"A manager doesn't win games by himself. It is his players. But if they like it then I hope they will carry on doing it because that means we will be successful."
Hou led the Reds out
Hou, Hou, Hou, Hou
2005 - Ring Of Fire
The reasons behind the hook of this Johnny Cash classic catching on during the journey to Istanbul were initially unclear - until one of the heroes of that run provided clarification, that is.
As Jamie Carragher once explained: "'Ring of Fire' started on the fans' coach that my dad and his mates get to the away games.
"Someone put a Johnny Cash tape on and my dad and everyone started singing it on the bus. It caught on at Anfield, then it became a favourite at the European away games."
The sight of thousands of red scarves whirling around the heads of disbelieving Reds became an iconic image of the club's fifth European Cup win.
That the back story of this chant has familial links to a keystone of the success makes it even better.
2007 - Oh Campione
Just two years on from 2005's miracle victory, the Reds were back in the Champions League final for a seventh time.
True to form, the club's supporters had taken a new song on tour across Europe en route to an Athens rematch with AC Milan.
And, despite that appearance in the competition's decisive fixture ending in disappointment, the Kop had a new addition to the songbook that still gets an outing to this day.
Oh, Campione
The one and only
We're Liverpool
They say our days are numbered, we're not famous anymore
But Scousers rule the country like we've always done before
2016 - Three Little Birds
This Bob Marley classic was initially sung in tribute to Liverpool fan Alex Jarmay, who was tragically killed in London ahead of the Reds' appearance in the 2012 League Cup final.
And it received a fresh outing during a memorable journey to the Europa League final in Jürgen Klopp's first season with the club.
The song picked up momentum as Manchester United, Borussia Dortmund and Villarreal were brushed aside, and a more defiant version was sung after defeat to Sevilla in the final.
Singin' don't worry about a thing,
'Cause every little thing gonna be all right
Singin' don't worry about a thing
'Cause every little thing gonna be all right