Stewart Downing and Martin Skrtel will reach career landmarks if selected to play against Manchester United on Sunday – find out about these and 19 other fascinating pre-match facts courtesy of club statto Ged Rea.
Martin Skrtel could play the 200th game of his Liverpool career in all competitions.
Stewart Downing could play the 300th league game of his career, while his only yellow card in his last 157 league appearances came at Old Trafford last season.
Liverpool's last win at Old Trafford came in March 2009 when Fernando Torres, Steven Gerrard (pen), Fabio Aurelio and Andrea Dossena all scored in a 4-1 win.
The last 10 league fixtures between Liverpool and United, home and away, have produced 33 goals.
Liverpool's biggest win at Old Trafford came in November 1936 when they beat United 5-2, closely followed by the 4-1 win in 2009.
There has not been a league draw between the sides at Old Trafford since March 2000, with Liverpool winning four and United eight of the subsequent 12 meetings.
The last five league meetings at Old Trafford have produced 19 goals.
Only Dick Forshaw (eight) and Harry Chambers and Gordon Hodgson (seven each) have scored more league goals for Liverpool against United than Steven Gerrard's six. Robbie Fowler also scored half a dozen.
Seven Liverpool players have scored league hat-tricks against Manchester United, with only two men - Peter Beardsley (1990) and Dirk Kuyt (2011) - achieving the feat in the last 75 years.
The last Liverpool player to score a hat-trick at Old Trafford was Fred Howe in November 1936.
Liverpool have scored in their last 10 games in league and cup since playing out a goalless draw at Swansea in late November.
Luis Suarez is one goal away from becoming the first Liverpool player since Fernando Torres in 2009-10 to score 20 goals in a season.
Daniel Sturridge is poised to make his league debut for Liverpool. His only goal against United came earlier this season in Chelsea's 5-4 League Cup win at Stamford Bridge.
United are the Premier League's leading scorers with 54 (13 more than their nearest rivals Manchester City) prior to this weekend's set of fixtures.
Only Everton and Norwich City have prevented United from scoring in the top-flight this season.
The last occasion they failed to score at home in the league was in December 2009 when Aston Villa - with Stewart Downing in the team - won 1-0. United have scored in all 59 home league games since - their longest ever scoring streak and the best in the top-flight by any team since Wolves' 75-match run from 1956-59.
Of their last 39 league games, United have lost just five.
United have been in front at half-time in 211 Premier League games at Old Trafford - they have never lost, having recorded 199 wins and 12 draws.
They have conceded the first goal 11 times in league games this season, coming from behind to win eight times.
Nemanja Vidic has been sent off three times against Liverpool - all in a 13-month spell during 2008-09.
Ryan Giggs is looking to score for the 23rd league campaign in succession. The Welshman, with 46, has made more appearances against Liverpool than any United player in history while Jamie Carragher with 33 has most for Liverpool against United.
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