Daniel Sturridge is set to make his 50th appearance for Liverpool in Sunday's season opener with Southampton at Anfield - here are all the facts and figures from club statistician Ged Rea.
Only George Allan, with 41, in the late 19th century has scored more goals in his first half century of games for the club than Sturridge, who currently has 36.
Last season on this ground, Southampton emerged victorious, winning 1-0 thanks to Dejan Lovren's 54th-minute winner. It was his first goal for the Saints.
In the return at St Mary's, Liverpool gained revenge with a comprehensive 3-0 victory thanks to goals from Luis Suarez, substitute Raheem Sterling and a last-minute Steven Gerrard penalty.
Liverpool's biggest Premier League victory came in January 1999 when they beat Southampton 7-1.
In the Premier League the sides have met 30 times - Liverpool winning 14 and Southampton nine. At Anfield, Liverpool have recorded eight wins, with three defeats and four draws.
Robbie Fowler is the only Liverpool player to score a hat-trick against the Saints. He did so twice, in October 1993 and January 1999.
Liverpool have failed to score in only five of the 49 meetings with the Saints at Anfield in all competitions.
The Reds won their opening game of last season, beating Stoke City 1-0 thanks to a goal from Sturridge. Simon Mignolet, on his debut, saved an 89th-minute penalty from Jon Walters.
This will be the seventh time in the last 19 seasons that the Reds have begun their league campaign with a home fixture. The Reds have only lost five of the last 38 opening day fixtures, but have won just one of the last five.
Liverpool finished last season's league campaign with a run of 13 wins, two draws and one defeat.
They suffered only two defeats at Anfield - to today's visitors and Chelsea. They were the only fixtures in which they failed to score a league goal in front of their own fans.
Liverpool have scored 96 goals in their last 34 league games after netting just five times in their opening four games of last season. They failed to score in only three of their 38 league fixtures in 2013-14.
Rickie Lambert is looking to maintain his record of scoring against every one of his former clubs, having found the net against Blackpool, Macclesfield, Stockport, Rochdale and Bristol Rovers.
Lambert played four times against Liverpool, with his only goal coming in a 3-1 home win at St Mary's in March 2013. He won two and lost two of those four meetings.
Adam Lallana played 265 times for the Saints in all competitions, scoring 60 times. He appeared in all three of England's World Cup games in Brazil this summer.
Lovren made 31 appearances for Southampton in his only season at St Mary's - netting twice.
Gerrard has scored 42 penalties for Liverpool - he is the joint all-time highest scorer from the spot with Jan Molby.
Liverpool scored a club record 59 first-half goals in the Premier League last season and their tally of 16 home wins was their best in the top flight since 1985-86.
The Saints are looking to record back-to-back league victories at Anfield for the first time in their history.
Southampton have won five of the last eight league meetings with the Reds home and away.
The Saints began last season with only one loss in the opening 11 league games, winning six of them and conceding just five goals.
They won 1-0 on the opening day thanks to a 90th-minute Lambert penalty at West Brom.
They completed last season unbeaten in four games, with Lambert scoring in the last two - a 1-0 victory at Swansea and a 1-1 home draw with Manchester United.
The only Southampton hat-trick against Liverpool was scored by Matthew Le Tissier at the Dell. His goals, including two penalties, saw his team claim all three points in a 4-2 win.
Last season Southampton finished eighth, equalling their previous Premier League best set in 2002-03. But the 56 points attained in the last campaign was four points better than that season under Gordon Strachan.
Ronald Koeman has won two of his six games against Liverpool as a coach. His Benfica team won both legs of a Champions League tie in 2006. He also faced the Reds four times while at the helm of PSV Eindhoven, also in the Champions League, suffering three defeats and drawing the other.