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Liverpool U21s host Patrick Vieira's Manchester City at the Kirkby Academy hoping to continue their excellent start to the season.
Michael Beale's side have won two games against Sunderland and West Ham with a 1-1 draw against Manchester United in between.
The last meeting between the two sides was on September 23, 2013, when an amazing goal from Adam Morgan was the highlight of a 2-0 win for the young Reds.
Kick-off in Kirkby is at 7pm BST.