Playing their first league game since October 21, Steven Gerrard's young Reds were full value for their victory.
Rafael Camacho, Liam Millar and Paul Glatzel were also on the mark.
Reflecting on his side's victory, Gerrard told Liverpoolfc.com: "We played some excellent stuff and controlled the game.
"I'm really proud of them because we were outstanding.
"We scored four excellent goals and we could have scored a few more as well. The lads are in a good place."
Liverpool U18s: Jaros, Sharif, Lewis (Larouci), R Williams, Glennon, Clayton, Dixon-Bonner, Tagseth, Millar (Glatzel), Jones (McAuley), Camacho.
LFCTV GO: The goals from the 5-1 win at Middlesbrough